Here’s How Glutathione, Oxidative Stress, and Mental Health Problems Are Somewhat Related

People suffering from mental health problems may feel hopeless at times but because of the continuous studies, many things have been said about how these developed. Experts have previously linked neurotransmitters and the conditions, which may help shed light on their connection.

Although more research needs to be done, there are recurring studies that say oxidative stress and depression and anxiety are associated. How did scientists know about this? The experts have noticed that people who were struggling with these mental health problems have low glutathione levels.

Glutathione and Mental Health

Researchers from the Weill Medical College of Cornell University and Icahn School of Medicine at Mount Sinai teamed up for a study on adolescent depression by using a spectroscopy, a test that analyzes biochemical changes in the brain.

The researchers observed depressed participants versus those without mental health problems and found that those facing psychological issues had significantly lower levels of glutathione.

There are other studies that mirror the same results. Another one noticed that animals with anxiety-like behaviors had a short supply of glutathione.

Oxidative Stress

This led the experts into thinking that oxidative stress plays a role in the development of these psychological issues. But how is it related to glutathione?

Oxidative stress is the imbalance of free radicals and antioxidants. Glutathione, meanwhile, is a marker of oxidative stress.

This means that when you have low levels of glutathione, you likely have used it up to fight free radicals, which are unstable and can damage healthy cells — the reason it is often associated with aging.

Despite this understanding, it remains unclear if supplying your body with glutathione may be the only trick we need to solve mental health problems.

Stress and Glutathione

We now know that oxidative stress and glutathione are related, but how about psychological stress?

Psychological stress involves what we feel when we have money problems or when we have an irritating officemate. Glutathione is mainly involved with chemical stress, which is a result of ingesting toxins.

Glutathione’s job is basically to deal with anything harmful in our bodies, like free radicals and heavy metals. Psychological stressors are typically addressed by adrenal glands that release the hormone cortisol.

However, if you reduce stress, you’re helping your body get the most out of glutathione. This is because the more stressed you are, the faster your heart rate is and the deeper you breathe, which are things that impede the detoxification of the body by the antioxidant.

Stress management and meditation may be a huge help in dealing with stress.